Steven Holdcroft. Science: Department of Chemistry. Thesis type:.
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Research process and sleep app design lessons learned from the reflective examination of a sleep study. The cells were encapsulated within a polysaccharide-based biogel to form a 3D construct interfaced with the CP pillar arrays and differentiated in situ with ES. The aim of the thesis was to provide a proof-of-concept of the ability to use fabricated 3D microelectrode arrays for electrical stimulation of neural tissues.
Hence, the thesis was aiming at validating the platform of 3D MEA chips with CP pillars on neuronal cultures and electrical stimulation and presenting the potential of the specific 3D MEAs with CP pillars for neurophysiological applications. This was achieved by fabricating 3D MEA chips with CP pillars and by using them in ES experiments differentiating clinically relevant cells which can be used for therapy related to neurological diseases and research.
The MEA chips were shown to allow the recording of extracellular potentials when electrophysiological signals were acquired from neuronal cultures.
The electrical stimulations of the cells provided with data revealing promising results related to the electrical activity of the cells. Off-Campus Purdue Users: To access this dissertation, please log in to our proxy server.
Where the concentration of buffering ions was low, it was found that a higher energy was required to perform the reduction reaction on the quinoid in the composite, without a change in pH. Volume 91 , Issue 1 5 January Pages This may take some time to load. RSS Feeds. Author Mohammad Yousef Al-Haik.
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Unless otherwise indicated, the views expressed in this thesis are those of the of conducting polymer coated textiles, Doctor of Philosophy thesis, Department. One of the aim of this study is to prepare conductive polymer nanocomposites of polypropylene to obtain better mechanical and electrical.
Advisors Boudouris, Purdue University. Subject Area Chemical engineering Materials science.
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